Search results for "Critical appraisal"
showing 10 items of 32 documents
Perspective: Essential study quality descriptors for data from nutritional epidemiologic research
2017
Pooled analysis of secondary data increases the power of research and enables scientific discovery in nutritional epidemiology. Information on study characteristics that determine data quality is needed to enable correct reuse and interpretation of data. This study aims to define essential quality characteristics for data from observational studies in nutrition. First, a literature review was performed to get an insight on existing instruments that assess the quality of cohort, case-control, and cross-sectional studies and dietary measurement. Second, 2 face-to-face workshops were organized to determine the study characteristics that affect data quality. Third, consensus on the data descrip…
Non-Small Cell Lung Cancer Harboring Concurrent EGFR Genomic Alterations: A Systematic Review and Critical Appraisal of the Double Dilemma
2021
The molecular pathways which promote lung cancer cell features have been broadly explored, leading to significant improvement in prognostic and diagnostic strategies. Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have dramatically altered the treatment approach for patients with metastatic non-small cell lung cancer (NSCLC). Latest investigations by using next-generation sequencing (NGS) have shown that other oncogenic driver mutations, believed mutually exclusive for decades, could coexist in EGFR-mutated NSCLC patients. However, the exact clinical and pathological role of concomitant genomic aberrations needs to be investigated. In this systematic review, we ai…
Steroids in Acute Spinal Cord Injury: All But Gone Within 5 Years.
2019
Background Spinal cord injury (SCI) is a devastating event often leading to poor neurologic outcomes. One of the most widely practiced treatments has been the administration of methylprednisolone. However, today its use has been called into question over concerns of efficacy and safety. The present study evaluated the changes in the practice of steroid administration in acute SCI among members of the National Spinal Society in Poland in comparison with the results of the survey conducted in 2013. Methods The questionnaire, comprising 5 questions, was distributed among 240 spinal surgeons, members of the Polish Society of Spinal Surgery; of these, 97 (40%) responded. The results were compare…
Young people with long-term health challenges experiences in transition to adulthood: A qualitative metasynthesis
2020
Author's accepted manuscript This is the peer reviewed version of the following article: Rasalingam, A., Fegran, L., Brekke, I. & Helseth, S. (2021). Young people with long-term health challenges experiences in transition to adulthood: A qualitative metasynthesis. Journal of Advanced Nursing, 77(2), 595-607 which has been published in final form at https://doi.org/10.1111/jan.14641. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislati…
Significant others’ experience of hospitalized patients’ transfer to home: A systematic review and meta-synthesis
2018
Abstract Background Significant others are individuals representing family members or neighbors, friends, colleagues or members of the same household, who act as relatives or surrogates. Significant others play an important role when patients are transferred or discharged after hospitalization. Objective The objective of this review is to identify, appraise and synthesize the best available evidence exploring significant others’ experiences of the discharge or transfer of adult patients after hospitalization. Methods A qualitative comprehensive systematic review and meta aggregation. Types of participants Participants of this review are the ‘significant other(s); persons who are important o…
A critical appraisal of capillary electrochromatography.
2002
Although still in its infancy, CEC promises some advantages over competitive techniques for separating charged analytes including biomolecules.
Meeting the environmental challenge of port growth: A critical appraisal of the contingent valuation method and an application to Valencia Port, Spain
2012
In order to support effective policy-making, this research is aimed to emphasise the need of measuring the negative impact - or external costs - resulting from port growth. Considering the non-market nature of these external costs, a critical appraisal of the Contingent Valuation method is made paying special attention to the problem of hypothetical bias and the suitability of a willingness to accept (WTA) scenario for damage assessment. Finally, the results of a case study, conducted in Valencia (Spain), are presented with the intention of paving the way for future research in this specific context of port growth and negative externalities. In particular, results indicate that the average …
The effect of pre-anaesthetic assessment clinic: a systematic review of randomised and non-randomised prospective controlled studies
2021
ABSTRACTObjectivesThe aim of this systematic review was to examine the effectiveness of pre-anaesthetic assessment clinics (PACs) implemented to improve quality and patient safety in perioperative care.DesignSystematic review.Data sourcesThe electronic databases CINAHL Plus with Full Text (EBSCOhost), Medline, and Embase (OvidSP) were systematically searched from 1st April, 1996 to 4th February, 2021.Eligibility criteriaThe main inclusion criterion was that the study, using empirical quantitative methods, addressed the effectiveness of PACs.Data extraction and synthesisTitles, abstracts, and full texts were screened in duplicate by two authors. Risk of bias assessment, using the Joanna Brig…
Biases in study design, implementation, and data analysis that distort the appraisal of clinical benefit and ESMO-Magnitude of Clinical Benefit Scale…
2021
BACKGROUND: The European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a validated, widely used tool developed to score the clinical benefit from cancer medicines reported in clinical trials. ESMO-MCBS scores assume valid research methodologies and quality trial implementation. Studies incorporating flawed design, implementation, or data analysis may generate outcomes that exaggerate true benefit and are not generalisable. Failure to either indicate or penalise studies with bias undermines the intention and diminishes the integrity of ESMO-MCBS scores. This review aimed to evaluate the adequacy of the ESMO-MCBS to address bias generated by flawed design, im…
Competence areas of health science teachers - A systematic review of quantitative studies.
2018
Abstract Background In the face of rapid digitalisation and ever-higher educational requirements for healthcare professionals, it is important that health science teachers possess the relevant core competences. The education of health science teachers varies internationally and there is no consensus about the minimum qualifications and experience they require. Objective The aim of this systematic review was to describe the health science teachers' competences and the factors related to it. Design Systematic review of original quantitative studies. Data sources Four databases were selected from which to retrieve original studies: Cinahl (Ebsco), PubMed, Medic, Eri (ProQuest). Review Methods …